| Address: |
25th Floor
MengMinwei Building
Nanjing University
Jiangsu Province
China
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| Tel: |
025-83592900
025-83595329 |
| Contact us: |
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| We focus on the area of soft matter and biophysics, including phase transitions and dynamics in complex fluids such as colloid and polymers, lateral organization in protein-membrane complexes, and nonequilibrium self-organization in living soft matter such as cellular cytoskeleton and self-propelled particles. The purpose of our group is to discover the real mechanism of self-assembly/self-organization of
soft materials under experimental observations and make some valuable predications to guide experiments. |
| 1ӢPhase Behaviors and Interactions in the Polymer-Colloid Complexes
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2ӢMembranes
Biomembranes are the interfaces that separate cells from the surrounding environments
and play an important role in cells. The main compositions of the membrane are lipids, proteins,
and so forth. Biomembrane is necessary for the realization of cell functions, such
as signal transduction and membrane trafficking. Therefore, understanding the structure,
organization of the membrane and the interplay between membranes and other
molecules is vitally essential. We focus on the physics of membrane systems.
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3.Investigation of Nonequilibrium
Systems of Active Matters
Active matter encompasses a wide variety of systems constituted by
running animals, flying birds, marching locusts, swimming bacteria, migrating cells,
driven granular rods and even cytoskeleton and molecular motor. It can be defined as a driven system. We focus on phase behaviors of these systems.
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4ӢComputer Simulations of Dendrimers and Their
Interactions with Bio(active) Molecules
There is a growing appreciation that an understanding of fundamental interactions
of nanoparticles with living matter will play a vital role in nanomedicine. Recently,
dendrimers, a class of soft nanoparticles, have received lots of attention owing to their
potential applications in biomedicine. Understanding their interactions with drugs, gene materials, and
the components of cell membranes is also significantly important to improve the targeting
efficiency of ”°drugs”±. We use molecular dynamics simulations to investigate
the related fields. |
5.Noise and Stochastic Dynamics in
Biochemical Systems
At the mesoscopic level, binding/unbindings that underlie processes, such as
gene expression, signal transduction, metabolism and molecular transport, are intrinsically
noisy. How to ensure reliable execution of the great variety of signaling, regulatory,
synthetic, and decision-making programs on top of noisy molecular circuits has
emerged as one of the fundamental issues in biological research. Experimental and theoretical
investigations of this question have prompted the birth of a new field of science
known as ”°noise biology”±. Our works focus on methodology and
formulation development, which can help to identify and understand the guiding principles
underling biochemical phenomena.
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